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serine n.【化學】絲胺酸。

seringa

There are at least three kinds of ep in petal : thiol - proteinase , metallo - proteinase , serine proteinase . they gather at the site between 43 kd and 66 . 2 kd ( about 52 kd ) on the substrate gel electrophoresis . the optimum ph of thiol - proteinase , metallo - proteinase is ph 6 , which are looked as acid ep , the serine proteinase has two forms , one is acid ep ( ph 6 ) , and the other is alkali ( ph 10 ) 花瓣中都至少有3種內肽酶:巰基蛋白酶、金屬蛋白酶、絲氨酸蛋白酶,三者聚集在底物膠電泳膠條的43kd 66 . 2kd之間的位置,約為52kd ;前兩種最適ph為6 ,是酸性內肽酶,后一種有酸( ph6 ) 、堿( ph10 )兩種存在形式,既是酸性內肽酶又是堿性內肽酶。

We obtained the full length gene of hbfgf coding sequence with pcr , and adjusted the g + c content according the software dnasisv2 . 5 , and replaced the cys78 and cys96 with serines by site - directed mutagenesis . 2 . sequence result suggested one of the recombinant is correctly synthezied and cloned 用pcr方法合成了hbfgf編碼區全長,其中前20個氨基酸的g + c含量按暨南大學碩士學位論文:大腸桿菌表達重組hbfgf結構和功能優化摘要照計算機軟件計算的結果進行了調整,第78和96位上的半瞇氨酸被突變為絲氨酸。

The he was strongly inhibited by sbti and apmsf , and very sensitive to pmsf , lbti , and tlck , while not sensitive to chymostatin , bestatin , leupeptin , tpck , pepstatin , nem and iam . all these results imply that brine shrimp he was most probably a trypsin - type serine protease . the he could be strongly inhibited by edta in a dose - dependent manner , and 50 mmol / l edta exhibited more than 56 . 5 % inhibition 對孵化酶純化樣品進行生化性質和酶性質分析發現,鹵蟲孵化酶的最適反應溫度約為40 ,最適ph為8 . 5左右;該孵化酶對p - apmsf 、 sbti極為敏感,對pmsf 、 lbti和tlck也非常敏感,但對chymostatin 、 leupeptin 、 pepstatin 、 bestatin 、 tpck 、 nem和iam不敏感,表明該酶極可能是一種屬于胰蛋白酶類型的絲氨酸蛋白酶。

Huwentoxin xi ( hwtx ~ xi ) , a serine protease ! inhibitor , consists of 55 amino acid residues with three disulfide bridges . the toxin was isolated from the venom of the chinese spider ornithochoctonus huwena by ion - exchange chromatogram - phy and reverse phase high performance liquid chromatography 本文報道從虎紋捕鳥蛛( ornithochoctonushuwena )粗毒中,應用陽離子交換和反相高效液相色譜的方法分離到一種胰蛋白酶抑制劑,命名為huwentoxin - ( hwtx - ) 。

The homologous analysis showed that the n - terminal sequence of dhap is identical to that of serine protease from another b . pumilus strain tyo - 67 and has high homology with those from other bacillus species . based on the homologous analysis , three pairs of primers were designed and synthesized 該序列與來自其它芽抱桿菌屬菌株的絲氨酸蛋白酶的n一末端氨基酸序列有較高的同源性,并和另一株短小芽抱桿菌的絲氨酸蛋白酶n一末端氨基酸序列完全一致。

8da and the content of cysteine is the highest which attain 22 . 2 % , following are lysine ( 8 . 0 ) and serine ( 7 . 7 % ) . however , there are aromatic amino acid residues and histidine in the amino acid sequence such as tyrosine ( 3 . 3 % ) , phenylalanine ( 3 . 0 % ) and histidine ( 2 序列中還含有少量的芳香族氨基酸,如酪氨酸( 3 . 3 ) ,苯丙氨酸( 3 . 0 )和組氨酸( 2 . 8 ) ,這一點和牡蠣mt相似,而不同于果蠅和哺乳動物mt (不含有芳香族氨基酸和組氨酸) 。

Usually , clr is binding to c1inh ( cl inhibitor ) . when immune complex ( ic ) binds to clq , c1inh is detached form clr , and then the serine protease is activated , and then the complement classical pathway is activated 在一般情況下, c1r與c1inh ( c1inhibitor )結合著,而一旦有免疫復合物( ic )結合到c1q上時,浙江大學碩士學位論文cllnh的抑制作用即行移除, clr的構象發生改變,具有酶活性,從而啟動補體激活經典途徑。

As a serine proteases , the expression product was detected with a relatively high protease activity . a similar result was also obtained from fibrin plate assay , it reveal ed that the expressed nk was provided with fibrinolytic activity 由于納豆激酶是一種蛋白酶,我們首先檢測并發現表達產物具有蛋白酶活性,通過纖維蛋白平板檢測表達產物具有溶圈活性,表明表達的納豆激酶具有溶解血栓的生物學功能。

6 . the ratio of acidic amino acids to basic amino acids is high in all of the spongy body , acid - sm and acid - ism . there are high contents of glycine ( gly ) and serine ( ser ) , which are usually related to the function of framework in the mineralization 6 、氨基酸分析表明酸性氨基酸含量較高,與鈣的吸附有關, gly和ser在背盾和不溶性有機質中高,預示與文石形成相關的膠原和纖維蛋白物質含量高。

Sequence alignment shows that the fragment of pcr product showed some identities to the masp gene of xenopus laevis , branchiostoma belcheri , the trypsin gene in litopenaeus vannamei and the serine protease gene in aurelia aurita Pcr反應產物基因片段大小為630bp ,序列比較結果表明, pcr克隆產物與爪蟾、文昌魚的masp基因,蝦、水母等的胰蛋白酶基因和絲氨酸蛋白酶基因都有一定的同源性。

The result of sequencing shows that this fragment contains an open reading frame of 1106 nucleotides and encodes 369 amino acids residues , which is part of a alkaline serine protease , with 98 . 3 % homogeneity to a reported gene from bacillus pumilus 序列分析顯示,該片段是一個全長1106bp的orf ,可編碼369個氨基酸殘基的多肽,與短小芽孢桿菌堿性蛋白酶基因編碼區高度同源。

The substance with antibacteria action obtained from forest frog is made up of alanine , aminoacetic acid , leucine , isoleucine , proline , aminoglutaric acid , threonine , serine , lysine . the substance with antibacteria action is a kind of poly peptide with a micromolecul 純化的林蛙皮膚抗菌活性物質經尿素? sds ? page電泳分析,表現為一條帶,分子量約為6 . 28kda 。

We confirmed one single nucleotide polymorphism ( snp ) site in the exon 7 of cd226 gene with agt - ggt polymorphism of 307 codon . among ten volunteers , 4 cases are serine and 6 cases are glycine at this codon 在編碼cd226胞漿區第307位氨基酸的密碼子上存在agt ? ggt單核昔酸多態性( singlenucleotidepolymorphism , snp ) ;分別編碼絲氨酸和甘氨酸。

Sorafenib , a novel , oral multi - kinase inhibitor , targets on serine / threonine and receptor tyrosine kinases of the tumor cells and vasculature ; blocks the signal transconduction and inhibits tumor growth 摘要索拉非尼是首個口服多激酶抑制藥,靶向作用于腫瘤細胞和腫瘤血管上的絲氨酸和(或)蘇氨酸及受體酪氨酸激酶,阻斷信號傳導,抑制腫瘤生長。

The term protein kinase c ( pkc ) stands for a group of at least twelve serine / threconine kinases that are characterized by a high degree of similarity in their catalytic kinase domains and cysteine - rich regions 前言蛋白激酶c ( pkc )是一組絲蘇氨酸蛋白激酶,參與多種信號傳導系統。包括細胞分化、生長調控、腫瘤發生和細胞凋亡。

On binding to specific carbohydrate structures on the surface of a broad range of microorganisms , mbl can activate complement system through the activation of mbl - associated serine proteases ( masps ) in antibody - and clq - independent way 甘露聚糖結合凝集素( mannan - bindinglectin , mbl )是c型凝集素超級家族中膠凝素家族成員。

The clsp protein shared roughly 25 - 40 % identity and 40 - 55 % similarity to complement subcomponent clr , cls , mannose - associated serine protease - 1 ( masp - 1 ) , masp - 2 , and masp - 3 通過在genba川k / embl數據庫中對clsp序列進行同源性搜索和分析,我們發現其核酸和氨基酸序列和人clr 、 cis 、 maspz 、 maspz 、 masp3等有高度同源性。

The kinase catalytic domain is 264 amino acids in length and contains all of 11 conserved subdomains and 15 invariant amino acid residues essential fo r eukaryotic serine / threonine protein kinases 激酶區長264個氨基酸殘基,具有所有11個保守的亞結構域和15個對于真核生物絲氨酸蘇氨酸蛋白激酶所必需的保守的氨基酸殘基。

Cdc25 undergoes serine / thre - onine phosphorylation at mitosis and enhances its phosphatase activity . mpf phosphorylates and actives cdc25 , which in turn dephosphorylates and further activates prempf Pkb分子量60kda ,目前已知分為pkb 、 、三種, pkb akt1廣泛存在于機體各組織中,其活性受多種激活劑調節。