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chemotactic adj.【生物學】趨化性的,趨藥性的。

chemotaxis

Chemotaxis mediated by chemokine receptors , such as cxcr4 , play a key role in lymphocyte homing and hematopoiesis as well as in breast cancer metastasis . we have previously demonstrated that ? - arrestin2 functions to attenuate cxcr4 - meidated g protein activation and to enhance cxcr4 internalization . here we further show that expression of ( - arrestin2 in both hela and hek293 cells significantly enhanced the chemotactic efficacy of stromal - cell derived factor 1 ( ( sdf - 1 ( ) , the specific agonist of cxcr4 - arrestin2是趨化因子受體的一種重要的調節蛋白,本研究工作發現在hek - 293或hela細胞中升高- arrestin2的表達水平會顯著增強cxcr4介導的趨化作用,反之當- arrestin2的表達被它的反義核苷酸或rnai所抑制, cxcr4介導的趨化作用則被明顯抑制。

Interestingly , inhibition of p38 mapk activation ( but not erk activation ) by its inhibitors or by expression of a dominant negative mutant of p38 mapk could effectively block the chemotactic effect of ( - arrestin2 P38mapk上游激酶ask1的顯性失活突變體也可以阻斷- arrestin2對趨化的增強作用。這說明是p38mapk而不是erk信號通路與- arrestin2對趨化的增強作用相關。

The spermatozoids of primitive plants are often positively chemotactic , swimming toward the female organs in response to a chemical secreted by the latter 較原始的植物的游動精子有正向的趨化現象,總是游向由雌性器官所分泌的物質。

Effects of urokinase - type plasminogen activator receptor on sperm chemotactic response induced by urokinase - type plasminogen activator in mice 尿激酶受體在尿激酶誘導小鼠精子趨化運動中的作用

Motile organisms may also be negatively chemotactic , swimming away from concentrations of toxic chemicals 可以游動的生物體也有負向的趨化現象,總是遠離有害的化學物質。

At very high doses of radiation , neutrophils failed to respond significantly to chemotactic stimuli 很高輻射劑量時,中性粒細胞對趨化刺激物無明顯反應。

Chemotaxis ( chemotactic movement ) a txis in response to a chemical concentration gradient 趨化現象:一種對化學濃度梯度的趨化反應。

Cf chemotactic factor 趨化因子

The inhibitory effect of hydrocortisone on the chemotactic migration of human leukocytes 氫化可的松對人白細胞趣化移動的抑制

Chemotactic peptide complement receptors 趨化肽補體受體